COMPARATIVE ANALYSIS AND SYSTEMATIZATION OF INTERNATIONAL AND NATIONAL CLINICAL GUIDELINES FOR THE MANAGEMENT OF POLYCYSTIC OVARY SYNDROME

Polycystic ovary syndrome (PCOS) is a complex endocrine disorder requiring evidence-based and standardized clinical management. Numerous international and national professional societies have developed clinical guidelines for PCOS; however, differences in diagnostic criteria and therapeutic approaches create challenges for clinical practice. Objective: To analyze and systematize current international and national clinical guidelines for the diagnosis and management of polycystic ovary syndrome, including recommendations from ESHRE, ACOG, and RARCh. Methods: An analytical review of official clinical guidelines published by leading international and national professional organizations was conducted. Diagnostic criteria, therapeutic strategies, and follow-up recommendations were systematically compared and structured according to clinical relevance. Results: Despite general consensus on core diagnostic principles, significant variability exists among guidelines regarding therapeutic prioritization, metabolic screening, and reproductive management. International guidelines emphasize individualized and multidisciplinary care, while national recommendations demonstrate adaptations to healthcare system capacities. Conclusion: Systematization of existing guidelines facilitates harmonization of clinical practice and supports the development of optimized, patient-centered management strategies for PCOS.