Urine metabolomic analyses reveal metabolite disruptions in steroid hormone biosynthesis in mpox

This data is the raw offline data of untargeted metabolomics in this study, including four groups of samples: MPXV group, HIV-MPXV group, HIV group, and healthy group. MPXV infection may affect the metabolic levels of patients. Through non targeted metabolomics techniques, it is known that mpox caused metabolic disorders in the body, especially downregulation of steroid hormone synthesis pathways.
This study used urine samples, mpox samples were collected from hospitalized patients, HIV samples were collected from outpatient clinics, and healthy samples were recruited from volunteers. All samples were collected within 2 months. Immediately freeze the collected samples in liquid nitrogen and store them in a -80 ° C freezer for later use. After all samples are collected, they will be inactivated in a biosafety level 3 laboratory and then packaged and stored for later use. By analyzing this raw data, identified metabolites and differential metabolites can be obtained.