Crystal structure of human calcium/calmodulin-dependent protein kinase kinase 2, beta, CaMKK2 kinase domain in complex with STO-609

Crystal structure of human calcium/calmodulin-dependent protein kinase kinase 2, beta, CaMKK2 kinase domain in complex with STO-609 Descriptor: 7-oxo-7H-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic acid, Calcium/calmodulin-dependent protein kinase kinase 2 Authors: Yoshikawa, S, Kukimoto-niino, M, Shirouzu, M, Suzuki, A, Lee, S, Minokoshi, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2008-10-31 Release date: 2009-11-03 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Crystal structure of the Ca2+/calmodulin-dependent protein kinase kinase in complex with the inhibitor STO-609 J.Biol.Chem., 286, 2011

人类钙/钙调蛋白依赖性蛋白激酶激酶2β亚型（CaMKK2）激酶结构域与STO-609结合的晶体结构。配体描述：7-氧代-7H-苯并咪唑并[2,1-a]苯并[de]异喹啉-3-羧酸。作者：Yoshikawa, S、Kukimoto-niino, M、Shirouzu, M、Suzuki, A、Lee, S、Minokoshi, Y、Yokoyama, S以及理化学研究所结构基因组学/蛋白质组学计划（RSGI）。提交日期：2008-10-31；发布日期：2009-11-03；最后修改日期：2023-11-01。实验方法：X射线衍射（分辨率2.4埃）。引用文献：《钙2+/钙调蛋白依赖性蛋白激酶激酶与抑制剂STO-609结合的晶体结构》，《J. Biol. Chem.》，286卷，2011年。