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Gene expression data from LCMV-specific WT and Ezh2-/- follicular T helper cells. Gene expression data from LCMV-specific WT and Ezh2-/- follicular T helper cells

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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA433813
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Microarray experiments were performed to elucidate the transcriptome changes due to EZH2 deficiency in follicular T helper (TFH) cells. These data suggest TFH-lineage associated genes are down-regulated in EZH2-null TFH cells, indicating that EZH2 primes TFH differentiation by regulating canonical genes of TFH cells. Overall design: WT and EZH2-null TFH cells (2 samples per group, each sample was pooled from at least 5 mice) were sorted at day 8-post LCMV Armstrong infection, followed by total RNA extracted and sent to microarray analysis.
创建时间:
2018-02-12
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