Topography parameters.

These are the command topography parameters programmed into the PES-1 system for each e-cig device. Since the device under test impacts the actual flow conditions seen by the device, the actual puff flow rate, duration, puff volume and cumulative case volumes were measured in a closed-loop feedback system. The results and subsequent analyses rely on the actual (measured) rather than the programmed (command) parameters. Each of these 10 cases was repeated for 6 trials for each e-cig product, e-liquid and power setting combinations listed in Table 2.