Ribosome profiling and mRNA sequencing of Drosophila oocytes during aging

NIAID Data Ecosystem2026-03-11 收录

卵母细胞衰老

mRNA翻译调控

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA573922 数据链接链接失效反馈

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资源简介：

This project studies the effects of aging on long lived mRNAs which are stored in transcriptionally inactive oocytes.

创建时间：

2019-09-24

Translational repression of the Drosophila nanos mRNA involves the RNA helicase Belle and RNA coating by Me31B and Trailer hitch

果蝇生物学

mRNA翻译调控

The maternal mRNA nanos is required for anterior-posterior patterning in the early Drosophila melanogaster development. The nanos-mRNA is translationally repressed and deadenylated during the first tw

NIAID Data Ecosystem90

Table_3_Systematic Understanding of Anti-Aging Effect of Coenzyme Q10 on Oocyte Through a Network Pharmacology Approach.xlsx

网络药理学

卵母细胞衰老

BackgroundMaternal oocyte aging is strongly contributing to age-related decline in female fertility. Coenzyme Q10 (CoQ10) exerts positive effects in improving aging-related deterioration of oocyte qua

NIAID Data Ecosystem60

Specific enhancement of the translation of thermospermine-responsive uORF-containing mRNAs by ribosomal mutations in Arabidopsis thaliana

植物信号转导

mRNA翻译调控

Auxin-induced xylem formation in angiosperms is negatively regulated by thermospermine, whose biosynthesis is also induced by auxin. In Arabidopsis thaliana, loss-of-function mutants of ACL5, which en

NIAID Data Ecosystem40

Source data for Figure 2 and Supplementary Figure 2

mRNA翻译调控

细胞基因表达

Source Data for Figure 2 and Supplementary Figure 2Fraction of translating, tethered mRNA per cell for Fig. 2DTranslation intensity of single mRNA for one experimental day for Fig. 2EIntensity of repo

Figshare2021-04-20 更新70

Induction of an alternative 5' leader enhances translation of Inpp5e and resistance to oncolytic virus infection. Induction of an alternative 5' leader enhances translation of Inpp5e and resistance to oncolytic virus infection

溶瘤病毒免疫机制

mRNA翻译调控

Residual cell-intrinsic innate immunity in cancer cells hampers infection with oncolytic viruses. Control of mRNA translation is an important feature of innate immunity, yet the identity of mRNA subst

NIAID Data Ecosystem50

Ribosome profiling and mRNA sequencing of Drosophila oocytes during aging

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