Temporal analysis of the T cell receptor (TCR) repertoire has been used to monitor treatment-induced changes in antigen-specific T cells in patients with cancer. However, the lack of experimental mode
To the right of each sequences is listed the number of Crohn’s disease (CD) or healthy control (HC) patients are shown who had that sequence in MAIT cells from their colon or blood. (XLSX)
PPD is a common component of hair dye, and can cause skin sensitisation and allergic contact dermatitis, where cutaneous inflammatory reaction in the latter is driven by both CD4+ and CD8+ T cells. Th
We developed an improved library prep protocol and standardized the data analysis pipeline for accurate repertoire profiling. In addition, two metrics were implemented to assess repertoire clone prope