Panel of cell radiosensitivity and mutation status.

A summary of all cell lines used in the present study. Surviving fraction of cells at 2 Gy (SF2) is used as a metric of radio-sensitivity, with SF2>0.6 considered a “resistant” line and SF2KRas, p53, and Keap1/Nrf2 is listed as either wildtype (wt) or mutated (mut) as determined by full exon sequencing (John Minna and Adi Gazdar, UT-Southwestern Medical Center, Dallas, TX, personal communications). A mutation is present in Keap1 in the NSCLC H23 cell line (personal communications with Brandon Probst, Reata Pharmaceuticals). “X” indicates experimentally manipulated gene expression.Panel of cell radiosensitivity and mutation status.