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资源简介：
Deep sequencing for off-target indel after treated by HELP
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创建时间：
2022-04-09
相关数据集
gene-editing experiments in model cell lines
gene-editing experiments to measure on/off-target modification of endogenous genomic loci using next-generation sequencing (GUIDE-SEQ)
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Additional file 1 of The genomes of precision edited cloned calves show no evidence for off-target events or increased de novo mutagenesis
Additional file 1: Table S1 Predicted and candidate off-target mutations.
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Linking CRISPR/Cas9 double-strand break profiles to gene editing precision with BreakTag [hiplex1]. Linking CRISPR/Cas9 double-strand break profiles to gene editing precision with BreakTag [hiplex1]
Here we developed BreakTag, a versatile, highly parallel and scissile-aware methodology for the profiling of Cas9-induced DNA double strand break (DSBs), to identify molecular determinants influencing
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High-throughput sequencing data of eeCas9 and eeBE of file6
Evaluation of the off-target efficiency of eeABEmax and ABEmax by HTS analysis in 293T cells.
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In vivo CRISPR-Cas gene editing with no detectable genome-wide off-target mutations
CRISPR-Cas genome-editing nucleases hold substantial promise for human therapeutics but identifying unwanted off-target mutations remains an important requirement for clinical translation. For ex vivo
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