Gene dosage alterations and correlating genes in locally advanced cervical cancer.

aPeak region of the recurrent gains and losses is the minimum shared region surrounded by at least three patients. In cases of recurrent high level amplification or homozygote deletion, this event determines the peak region. Peak region of the predictive losses is the region selected by LASSO.
bFrequency is the median percentage of tumors with the alteration.
cGene dosage is absolute DNA copy number divided by ploidy. Maximum (gain) or minimum (loss) gene dosage and corresponding copy number are listed.
dGenes within the peak region showing a correlation between gene dosage and expression are ordered by DNA location.
eRecurrent high level amplification detected within recurrent gain. Peak region is the region with more than 25% higher amplitude than surrounding region.
fProbably two different peak regions.
gHomozygote deletion within recurrent loss. Peak region is the region with a gene dosage of zero.