Circular RNA expression signature of low-glucose-treated MIA PaCa-2 cells

Glucose metabolism makes contributions to the development of pancreatic ductal adenocarcinoma (PDAC). Meanwhile, circular RNAs, a subset of noncoding RNAs, plays an important role in glucose metabolism and cancer progression. Analysis of low-glucose-treated and normal-glucose-treated MIA PaCa-2 cells from 6 samples (3 samples each group) was conducted. Results indicate insight into molecular signature of the pathogenesis of PDAC in abberant glucose metabolism. High throughput sequencing analysis was conducted to identify the differentially expressed circular RNAs between low-glucose-treated and normal-glucose-treated MIA PaCa-2 cells from 6 samples.