Drug-protein conjugates--XII. A study of the disposition, irreversible binding and immunogenicity of penicillin in the rat.
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Rats immunized with BPO-KLH made both IgM and IgG antibodies to BPO. Immunization with the larger dose (200 ug/kg vs. 20 ug/kg) led to higher titers. Immunization with benzyl penicillin alone did not lead to detectable antibody formation.
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1987-01-01



