Results from the meta-analysis, replication, and combined analysis.
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https://figshare.com/articles/dataset/_Results_from_the_meta_analysis_replication_and_combined_analysis_/472736
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The meta-analysis was performed using a directional non-weighed Z-score method as explained in the methods section. Combined analyses were performed using a directional weighed Z-score method within diseases and a directional non-weighed Z-score method between diseases. Results for the combined analysis are given only for the SNPs that pass the replication thresholds (directionality in each disease and p-value <0.0071 for the combined replication data).
*, IL18RAP and PTPN2 were not followed up because they are known shared risk loci for CD and CelD;
**, OR for the replication is reported for the allele identified as the risk allele in the initial scan;
#, SNPs that were imputed in the CelD replication datasets.
N.T., not tested. CelD = Celiac disease, CD = Crohn's disease, SNP = single nucleotide polymorphism, IL18RAP = interleukin 18 receptor accessory protein, PTPN2 = protein tyrosine phosphatase, PUS10 = pseudouridylate synthase 10, CCDC91 = coiled-coil domain containing 91, TAGAP = T-cell activation RhoGTPase activating protein, KCNG4 = potassium voltage-gated channel, subfamily G, member 4, non-receptor type 2, C10orf72 = Chromosome 10 open reading frame 72, FERMT1 = - fermitin family homolog 1, 3q13, 9q13, 17p13 = intergenic regions.
创建时间:
2011-01-27



