UniPep

There has been considerable recent interest in proteomic analyses of plasma for the purpose of discovering biomarkers. Profiling N-linked glycopeptides is a particularly promising method because the population of N-linked glycosites represents the proteomes of plasma, the cell surface, and secreted proteins at very low redundancy and provides a compelling link between the tissue and plasma proteomes. Here, we describe UniPep, a database of human N-linked glycosites - as a resource for biomarker discovery.

搜集汇总

背景与挑战

背景概述

Unipep是一个蛋白质组学数据集项目，提供来自瑞士联邦理工学院和系统生物学研究所的数据访问。初始阶段专注于潜在糖肽库，包含NxS/T基序的肽段，通过LC/MSMS实验和理论数据库映射；未来计划扩展至原型肽段存储库。