TBK1 in complex with compound 2

TBK1 in complex with compound 2 Descriptor: Serine/threonine-protein kinase TBK1, ~{N}-(cyclopropen-1-ylmethyl)-2-[[4-[[4-[3,3,3-tris(fluoranyl)propanoyl]piperazin-1-yl]methyl]pyridin-2-yl]amino]-1~{H}-benzimidazole-5-carboxamide Authors: Panne, D, Hillig, R.C, Rengachari, S. Deposit date: 2019-05-22 Release date: 2020-01-01 Last modified: 2024-05-15 Method: X-RAY DIFFRACTION (3.15 Å) Cite: Discovery of BAY-985, a Highly Selective TBK1/IKK epsilon Inhibitor. J.Med.Chem., 63, 2020化合物2复合物中的TBK1 描述项：丝氨酸/苏氨酸蛋白激酶TBK1（Serine/threonine-protein kinase TBK1），N-(环丙烯-1-基甲基)-2-[[4-[[4-[3,3,3-三氟丙酰基]哌嗪-1-基]甲基]吡啶-2-基]氨基]-1H-苯并咪唑-5-甲酰胺。作者：Panne D、Hillig R.C、Rengachari S。沉积日期：2019-05-22；发布日期：2020-01-01；最后修改日期：2024-05-15。实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率3.15埃（Å）。引用文献：《BAY-985：一种高选择性TBK1/IKKε抑制剂的发现》，J.Med.Chem., 63, 2020