RNA-seq of murine CD8+ tumor-infiltrating T cells following treatment with pembrolizumab and/or ABL503
收藏NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE264650
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We aimed to analyze the transcriptomic changes in CD8+ tumor-infiltrating T cells induced by anti-PD-1 treatment and/or anti-PD-L1x4-1BB bispecific antibody treatment C57BL/6 hPD-1/hPD-L1/h4-1BB mice were inoculated with syngeneic MC38 tumor cells overexpressing human PD-L1. When the mean tumor volume reached 150–200 mm3, the mice were randomly grouped to receive the treatment. At day 4 after the treatment, CD8+ TILs were sorted.
创建时间：
2024-04-30
