Background Thousands of mammalian promoters are defined by co-enrichment of the histone tail modifications H3K27me3 (repressive) and H3K4me3 (activating) and are thus termed bivalent. It was previousl
While enhancers are often regulated at the level of accessibility by pioneer factors, promoters tend to be constitutively accessible and poised for activation by paused Pol II â thus are often not c
Solution structure of the complex formed by the region 2 of E. coli sigmaE and its cognate -10 promoter element non template strand TGTCAAA. Descriptor: DNA, RNA polymerase sigma factor Authors: Campa
Alternative promoter is a potentially proteome-expanding mechanism by which multiple pre-mRNAs are transcribed from a single gene. However, its general impact on the proteome and whether this regulati
