NiCl2 as a Cheap and Efficient Precatalyst for the Coupling of Aryl Fluorosulfonate and Phosphite/Phosphine Oxide

conclusions, We have developed a nickel-catalyzed coupling of aryl fluorosulfonates and phosphine oxides/phosphites. The using of NiCl₂ as a cheap pre-catalyst and avoidance of additives enable this transformation more practical. The tolerance of functional group is good, and the late-stage conversion of estrone is achieved.