Effect of KHSRP KO in adult mouse neocortex (CTX)

This study explores whether KHSRP deletion could affect the levels of mRNAs and lncRNAs in the mouse cortex Total RNA from adult male mice (2-4 months old) was isolated using the Trizol method following by RNA precipitation with ethanol and quantitation of the resuspended RNA using Qubit and Nanodrop. RNA (1 microgram) was shipped to Arraystar to be analyzed using GPL25015 Arraystar Mouse LncRNA microarray V3B (Agilent-055750 custom Probe Name version) RNA isolation were run in triplicates using 3 KHSRP KO and 3 wild type (WT) mice from the same litter that generated the KHSRP KO mice