It’s crucial to identify novel protein biomarkers and therapeutic targets for Graves' disease (GD) and Graves' ophthalmopathy (GO). Based on large-scale circulating proteomic data from the UK Biobank
Protein kinases are key signaling enzymes that catalyze the transfer of γ-phosphate from an ATP molecule to a phospho-accepting residue in the substrate. Unraveling the molecular features that govern
Owing to its clinical significance, modulation of functionally relevant amino acids in protein-protein complexes has attracted a great deal of attention. To this end, many approaches have been propose