Data and most relevant results for the FoldDock project

Data and main results for the study <b>"Improved prediction of protein-protein interactions using AlphaFold2 and extended multiple-sequence alignments."</b><b></b><br>Contained datasets consist of:<b>1 -</b> 219 heterodimers from dockground benchmark 4 dataset <b>2 -</b> 1503 heterodimeric structures from a recent study (Green, A. G. et al. Nat. Commun. 12, 1–12 (2021))<b>3 -</b> 7 heterodimeric complexes from CASP14<b>4 -</b> 8 novel heterodimeric complexes deposited in the PDB database after 15 June 2021<br>For each one of the mentioned datasets it can be found in this repository:- concatenated protein sequences in FASTA format;- 3D structure atomic coordinates in PDB format;<br>- csv files summarizing chain IDs, chain lengths and other dataset parameters;- msas for pair of sequences, required to run AlphaFold2<br><br>For dataset 1 and 2, AlphaFold2 output docking results for 5 identical runs are provided as well, together with a csv summarizing dockq scores and different model quality metrics.<br>