Human transthyretin (TTR) complexed with (Z)-5-(3,5-dibromo-4-hydroxybenzylidene)-imino-1-methylimidazolidin-4-one

Human transthyretin (TTR) complexed with (Z)-5-(3,5-dibromo-4-hydroxybenzylidene)-imino-1-methylimidazolidin-4-one Descriptor: (5Z)-2-amino-5-(3,5-dibromo-4-hydroxybenzylidene)-1-methyl-1,5-dihydro-4H-imidazol-4-one, Transthyretin Authors: Connelly, S, Wilson, I.A. Deposit date: 2010-10-05 Release date: 2011-08-24 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Potent kinetic stabilizers that prevent transthyretin-mediated cardiomyocyte proteotoxicity. Sci Transl Med, 3, 2011

与(Z)-5-(3,5-二溴-4-羟基亚苄基)-亚氨基-1-甲基咪唑烷-4-酮结合的人类运甲状腺素蛋白（transthyretin, TTR）复合物。描述项：(5Z)-2-氨基-5-(3,5-二溴-4-羟基亚苄基)-1-甲基-1,5-二氢-4H-咪唑-4-酮、运甲状腺素蛋白。作者：Connelly, S、Wilson, I.A.。沉积日期：2010-10-05；发布日期：2011-08-24；最后修改日期：2023-09-06。实验方法：X射线衍射（X-RAY DIFFRACTION，分辨率1.6 Å）。引用文献：《可预防运甲状腺素蛋白介导的心肌细胞蛋白毒性的强效动力学稳定剂》，《科学·转化医学（Sci Transl Med）》，第3卷，2011年。