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NFAT transcriptional activity is associated with metastatic capacity in colon cancer

ChEBI2014-10-21 更新2026-07-21 收录

结肠癌转移机制

NFAT转录因子

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-38832 数据链接链接失效反馈

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NFAT transcriptional activity is associated with metastatic capacity in colon cancer

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创建时间：

2014-10-21

TCR信号传导

NFAT转录因子

Nuclear factor of activated T cells (NFAT) transcription factors are required for induction of T-cell cytokine production and effector function. Although it is known that activation via the T-cell ant

NIAID Data Ecosystem50

A Key Role of microRNA-29b for the Suppression of Colon Cancer Cell Migration by American Ginseng

结肠癌转移机制

miRNA调控抗癌

Metastasis of colon cancer cells increases the risk of colon cancer mortality. We have recently shown that American ginseng prevents colon cancer, and a Hexane extract of American Ginseng (HAG) has pa

NIAID Data Ecosystem30

TMED9-gated CNIH4 and TGFa signaling promotes pro-metastatic states in human primary colon cancer cells

结肠癌转移机制

肿瘤信号通路

How cells in primary tumors initially become pro-metastatic is not understood. A previous genome-wide RNAi screen uncovered colon cancer metastatic suppressor and WNT promoting functions of TMED3, a m

NIAID Data Ecosystem20

Metastasis of colon cancer requires Dickkopf-2 to generate cancer cells with Paneth cell properties

结肠癌转移机制

癌症干细胞特征

Metastasis is the leading cause of cancer-related mortality. Cancer stem cells contribute to metastasis in the murine colon cancer models, but the underlying mechanisms are unclear. Here we report a W

NIAID Data Ecosystem30

Zymosan stimulation of MyD88-deficient bone marrow-derived macrophages

Dectin-1

NFAT转录因子

Innate immune pattern recognition receptors play critical roles in pathogen detection and initiation of antimicrobial responses. We and others have previously demonstrated the importance of the beta-g

NIAID Data Ecosystem30

NFAT transcriptional activity is associated with metastatic capacity in colon cancer

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