P38 Signaling

NIAID Data Ecosystem2026-05-10 收录

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This representation depicts some of the pathways leading to p38/MAPK14 activation during inflammation or upon TGF-beta stimulation. P38 is activated also in other circumstances such as DNA damage, heat shock, osmotic stress or myogenesis.

创建时间：

2025-11-26

Supplementary Material for: Inhibition of p38mapk Reduces Adipose Tissue Inflammation in Aging Mediated by Arginase-II

炎症研究

p38 MAPK信号通路

Background: Adipose tissue inflammation occurs not only in obesity but also in aging and is mechanistically linked with age-associated diseases. Studies show that ablation of the l-argin

DataCite Commons2020-08-25 更新110

The Mitogen-Activated Protein Kinase p38α Regulates Tubular Damage in Murine Anti-Glomerular Basement Membrane Nephritis

肾脏炎症

p38 MAPK信号通路

p38 mitogen-activated protein kinase (MAPK) is thought to play a central role in acute and chronic inflammatory responses. Whether p38MAPK plays a pathogenic role in crescentic GN (GN) and which of it

NIAID Data Ecosystem70

Activation of p38 Mitogen-Activated Protein Kinase by Sodium Salicylate Leads to Inhibition of Tumor Necrosis Factor-Induced IκBα Phosphorylation and Degradation

p38 MAPK信号通路

抗炎药物机制

Many actions of the proinflammatory cytokines tumor necrosis factor (TNF) and interleukin-1 (IL-1) on gene expression are mediated by the transcription factor NF-κB. Activation of NF-κB by TNF and IL-

PubMed Central30

Fig.4 and Fig.6 (qRT-PCR).xlsx

基因表达分析

p38 MAPK信号通路

qRT-PCR was performed to analyze the relative expression of four candidate genes related to p38 MAPK signaling pathway. (A) NGF, (B) DDIT3, (C) GADD45A, and (D) FGF2. (n = 3 samples per group, *P

NIAID Data Ecosystem80

C-type natriuretic peptide regulates endochondral ossification through p38 MAP kinase-dependent pathways_2

软骨内骨化

p38 MAPK信号通路

C-type natriuretic peptide (CNP) has been recently identified as an important anabolic regulator of endochondral bone growth, but the molecular mechanism mediating these effects are not completely und

NIAID Data Ecosystem50

P38 Signaling

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