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E. coli TS Complex with dUMP and the Pyrrolo(2,3-d)pyrimidine-based Antifolate LY341770

NIAID Data Ecosystem2026-05-02 收录

胸苷酸合成酶

抗叶酸药物设计

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E. coli TS Complex with dUMP and the Pyrrolo(2,3-d)pyrimidine-based Antifolate LY341770

应用场景：

创建时间：

2024-11-13

抑制剂结构

抗叶酸药物设计

E. coli dihydropteroate synthase complexed with an 8-mercaptoguanine derivative: 2-azanyl-8-[(2-fluorophenyl)methylsulfanyl]-1,9-dihydropurin-6-one Descriptor: 2-azanyl-8-[(2-fluorophenyl)methylsulfan

Protein Data Bank Japan2023-10-04 更新50

6-substituted pyrido[3,2-d]pyrimidine--6-4'-trifluoromethoxyphenyl)

药物靶点结构

抗叶酸药物设计

6-substituted pyrido[3,2-d]pyrimidine--6-4'-trifluoromethoxyphenyl) Descriptor: Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, N~6~-methyl-N~6~-[4-(trifluoromethox

Protein Data Bank Japan2023-09-27 更新40

THYMIDYLATE SYNTHASE R179E MUTANT

胸苷酸合成酶

药物靶点研究

THYMIDYLATE SYNTHASE R179E MUTANT

NIAID Data Ecosystem30

Structure of Dihydrofolate reductase from Mycobacterium tuberculosis in complex with NADPH and pemetrexed

结核病药物靶点

抗叶酸药物设计

Structure of Dihydrofolate reductase from Mycobacterium tuberculosis in complex with NADPH and pemetrexed Descriptor: 2-{4-[2-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-5-YL)-ETHYL]-BENZOYL

Protein Data Bank Japan2024-03-13 更新40

Crystal structure of thymidylate synthase from shrimp

胸苷酸合成酶

药物靶点分析

Crystal structure of thymidylate synthase from shrimp Descriptor: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, TOMUDEX, Thymidylate synthase Authors: Ma, Q, Zang, K, Liu, C. Deposit date: 2019-06-08 Release date

Protein Data Bank Japan2023-11-22 更新40

E. coli TS Complex with dUMP and the Pyrrolo(2,3-d)pyrimidine-based Antifolate LY341770

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