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Identification of a HTT-specific binding motif in DNAJB1 essential for suppression and disaggregation of HTT

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NIAID Data Ecosystem2026-03-13 收录
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https://zenodo.org/record/6365425
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Underlying data of the in silico work performed in this study.  1. i-Tasser predictions for HTTExon1Q48  2. HDOCK results of DNAJB1-HTTExon1Q48 docking 3. TIGER2h structures and trajectories. The original data and filtered trajectories for the individual clusters 4. MD Simulation structures and trajectories for DNAJB1 protein variants alone and as complexes with HTTExon1Q48.
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2022-04-08
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