Clinical findings in SHIV-infected rhesus monkeys challenged with ZEBOV.
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Fever is defined as a temperature more than 2.5 °F over baseline or at least 1.5 °F over baseline and ≥103.5 °F.Mild rash: focal areas of petechiae covering less than 10% of the skin; moderate rash: areas of petechiae covering between 10% and 40% of the skin; severe rash: areas of petechiae and/or echymosis covering more than 40% of the skin.Lymphopenia and thrombocytopenia defined by ≥35% drop in numbers of lymphocytes and platelets, respectively.Alkaline phosphatase (ALP), alanine aminotransferase (ALT), aspartate aminotransferase (AST), gamma-glutamyltransferase (GGT), blood urea nitrogen (BUN), creatinine (CRE), uric acid (UA), Albumin (ALB), Amylase (AMY), Glucose (GLU).↑ = 2–3 fold increase; ↑↑ = 4–5 fold increase; ↑↑↑ = >5 fold increase; ↓ = 2–3 fold decrease.( ) Days after ZEBOV challenge are shown in parentheses.
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2015-12-03



