Crystal structure of thioredoxin gluthathione reductase from Schistosoma japonicum with the U597C mutation in complex with GSH
收藏Protein Data Bank Japan2026-05-27 更新2026-05-09 收录
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Crystal structure of thioredoxin gluthathione reductase from Schistosoma japonicum with the U597C mutation in complex with GSH Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Glutathione, SODIUM ION, ... Authors: Wang, S.Q, Huang, S.Q, Lin, T.W. Deposit date: 2026-01-08 Release date: 2026-04-15 Last modified: 2026-05-27 Method: X-RAY DIFFRACTION (2.12 Å) Cite: Structural basis for substrate recognition and inhibition of thioredoxin glutathione reductase from Schistosoma japonicum: Implications for antiparasitic development. Plos Pathog., 22, 2026
日本血吸虫(Schistosoma japonicum)来源携带U597C突变的硫氧还蛋白谷胱甘肽还原酶(thioredoxin glutathione reductase)与谷胱甘肽(GSH)的复合物晶体结构
描述:黄素腺嘌呤二核苷酸、谷胱甘肽、钠离子……
作者:Wang S.Q.、Huang S.Q.、Lin T.W.
提交日期:2026-01-08
发布日期:2026-04-15
最后修改日期:2026-05-27
实验方法:X射线衍射(2.12埃)
引用文献:《日本血吸虫硫氧还蛋白谷胱甘肽还原酶的底物识别与抑制结构基础:抗寄生虫开发的启示》,《PLOS Pathogens》,2026年,第22卷
创建时间:
2026-01-08



