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Parallel characterization of cis-Regulatory Elements for Multiple Genes using CRISPRpath. Parallel characterization of cis-Regulatory Elements for Multiple Genes using CRISPRpath

NIAID Data Ecosystem2026-03-12 收录

植物顺式调控元件分析

CRISPRi筛选

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA702095 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

应用场景：

创建时间：

2021-02-16

抗体生产优化

CRISPRi筛选

Mammalian cells are used to express complex biologics, such as multispecific antibodies. While multispecifics enable promising new strategies for treating human disease, their production at high expre

NIAID Data Ecosystem30

Genome-scale CRISPRi Perturb-seq on both unstimulated and stimulated Jurkat cells reveals regulators of human T-cell signaling

T细胞信号传导调控

CRISPRi筛选

The goal of the experiment is to identify genes involved in T-cell receptor (TCR) signaling and T-cell activation in human T cells. The Jurkat E6 cell line, engineered to express dCas9-KRAB and transd

NIAID Data Ecosystem20

Essential gene profiles for human pluripotent stem cells identify uncharacterized genes and substrate dependencies. Mair et al.

干细胞鉴定

CRISPRi筛选

Human pluripotent stem cells (hPSCs) provide an invaluable tool for modeling diseases and hold promise for regenerative medicine. For understanding pluripotency and lineage differentiation mechanisms,

NIAID Data Ecosystem20

Bcor loss perturbs myeloid differentiation and promotes leukaemogenesis [TargetedCRISPRscreen]

白血病发病机制

CRISPRi筛选

Investigating Bcor target genes in BcorΔE9-10KrasG12D leukaemia with a custom CRISPR dropout screen BcorΔE9-10KrasG12D cell line was transduced with a custom CRISPR library and a dropout screen was pe

NIAID Data Ecosystem30

Human cortical organoids with engineered microglia-like cells [CROP-seq]

神经退行性疾病模型构建

CRISPRi筛选

Microglia play vital roles in the emergence and preservation of a healthy brain microenvironment with their impaired functions highlighted in neurodevelopmental and neurodegenerative disorders. Howeve

NIAID Data Ecosystem20

Parallel characterization of cis-Regulatory Elements for Multiple Genes using CRISPRpath. Parallel characterization of cis-Regulatory Elements for Multiple Genes using CRISPRpath

资源简介：

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