Crystal structure of Zika NS2B-NS3 protease in complex with follow-up compound EOS90861 from ECBL

Crystal structure of Zika NS2B-NS3 protease in complex with follow-up compound EOS90861 from ECBL Descriptor: 3-[[[(2~{R})-2-[2,4-bis(fluoranyl)phenyl]-2-oxidanyl-ethyl]amino]methyl]quinolin-2-ol, Genome polyprotein, Serine protease subunit NS2B Authors: Benz, L.S, Wollenhaupt, J, Jirgensons, A, Miletic, T, Mueller, U, Weiss, M.S. Deposit date: 2025-06-06 Release date: 2025-10-29 Last modified: 2025-12-24 Method: X-RAY DIFFRACTION (1.58 Å) Cite: From fragments to follow-ups: rapid hit expansion by making use of EU-OPENSCREEN resources. Rsc Med Chem, 16, 2025