FOXM1 Orchestrates a Global Methylation Signature that Mimics the Cancer Epigenome

ChEBI2012-04-18 更新2026-07-21 收录

癌症表观遗传学

甲基化调控

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-31767 数据链接链接失效反馈

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FOXM1 Orchestrates a Global Methylation Signature that Mimics the Cancer Epigenome

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2012-04-18

Global 5mC and 5hmC levels in sixteen pairs of HCC and non-HCC samples and two HCC cell lines investigated by UPLC-MS/MS

癌症表观遗传学

甲基化测序

We performed UPLC-MS/MS to investigate global 5mC and 5hmC levels in sixteen pairs of HCC and non-HCC samples and two HCC cell lines (97L and LM6 cells). We found that 5mC and 5hmC were frequently dec

Figshare2016-01-19 更新70

Prevention of chromatin destabilization by FACT is crucial for malignant transformation. Prevention of chromatin destabilization by FACT is crucial for malignant transformation

癌症表观遗传学

染色质动力学

Histone chaperone FACT is commonly expressed and essential for the viability of transformed but not normal cells and its expression levels correlate with poor prognosis in cancer patients. FACT binds

NIAID Data Ecosystem40

Summary of OPCML methylation in cell lines and primary tumors.

癌症表观遗传学

DNA甲基化分析

Summary of OPCML methylation in cell lines and primary tumors.

NIAID Data Ecosystem30

Epigenomic study identifies a novel mesenchyme homeobox2-GLI1 transcription axis involved in cancer drug resistance, overall survival and therapy prognosis in lung cancer patients

癌症表观遗传学

药物耐药性

Several homeobox-related gene (HOX) transcription factors such as mesenchyme HOX-2 (MEOX2) have previously been associated with cancer drug resistance, malignant progression and/or clinical prognostic

DataONE2020-06-24 更新60

Dynamic imbalance between cancer cell subpopulations induced by Transforming Growth Factor Beta (TGF-β) is associated with a DNA methylome switch [methylation]

癌症表观遗传学

癌细胞异质性

Distinct subpopulations of neoplastic cells within tumors, including hepatocellular carcinoma (HCC), display pronounced ability to initiate new tumors and induce metastasis. Recent evidence suggests t

NIAID Data Ecosystem40

FOXM1 Orchestrates a Global Methylation Signature that Mimics the Cancer Epigenome

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