USP7 in complex with GNE6776 (6'-amino-4'-ethyl-5'-(4-hydroxyphenyl)-N-methyl-[3,3'-bipyridine]-6-carboxamide)

USP7 in complex with GNE6776 (6'-amino-4'-ethyl-5'-(4-hydroxyphenyl)-N-methyl-[3,3'-bipyridine]-6-carboxamide) Descriptor: 6'-amino-4'-ethyl-5'-(4-hydroxyphenyl)-N-methyl[3,3'-bipyridine]-6-carboxamide, Ubiquitin carboxyl-terminal hydrolase 7 Authors: Murray, J.M, Rouge, L. Deposit date: 2017-02-08 Release date: 2017-10-25 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.23 Å) Cite: USP7 small-molecule inhibitors interfere with ubiquitin binding. Nature, 550, 2017泛素羧基末端水解酶7（USP7，Ubiquitin carboxyl-terminal hydrolase 7）与GNE6776（6'-氨基-4'-乙基-5'-(4-羟基苯基)-N-甲基-[3,3'-联吡啶]-6-甲酰胺）的复合物。描述符：6'-氨基-4'-乙基-5'-(4-羟基苯基)-N-甲基-[3,3'-联吡啶]-6-甲酰胺，泛素羧基末端水解酶7（USP7） 作者：Murray, J.M、Rouge, L. 保藏日期：2017-02-08 发布日期：2017-10-25 最后修改日期：2023-10-04 实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率2.23埃（Å） 引用文献：USP7小分子抑制剂可干扰泛素结合。《自然》（Nature），550卷，2017年