Odds ratios (ORs) and 95% confidence intervals (CIs) of cardiovascular mortality by serum GPx 3 activity.

*Shown are the year-specific quartiles of GPx3 activity, based on the distribution in controls. Ranges of GPx3 activity in U/ml for increasing quartiles were 0.09–0.23, 0.24–0.30, 0.31–0.42, and 0.43–0.76 in 1990–1992, and 0.17–0.35, 0.36–0.47, 0.48–0.56, and 0.57–1.03 in 1995–1997. The highest quartile of GPx3 activity (quartile 4) was used as the referent.‡Shown are regression coefficients (standard errors) predicting the case-control logit per standard-deviation (0.16 U/ml) increase of GPx3 activity.§Adjusted for matching factors age (continuous) and sex, and baseline year.∥Adjusted as in model 1, but with additional adjustment for body mass index (continuous), current cigarette smoking, alcohol use (dummy variables in drinks per week: 1–6, 7–14, >14), and physical activity (continuous).¶Adjusted as in model 2, but with additional adjustment for total cholesterol (continuous), HDLc (continuous), systolic blood pressure (continuous), non-fasting glucose (continuous), and GGT (continuous). In stratified analysis, adjustment for HDLc was omitted.**Low HDLc was defined as lower than the median serum value of 38 mg/dl for men and 48 mg/dl for women, high serum HDLc as greater or equal to 38 mg/dl in men and 48 mg/dl in women.