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S. aureus DHFR complexed with NADPH and folate

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Protein Data Bank Japan2024-03-20 更新2026-03-21 收录
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S. aureus DHFR complexed with NADPH and folate Descriptor: DIHYDROFOLIC ACID, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Authors: Oefner, C, Dale-Glenn, E. Deposit date: 2009-01-08 Release date: 2010-01-12 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Increased hydrophobic interactions of iclaprim with Staphylococcus aureus dihydrofolate reductase are responsible for the increase in affinity and antibacterial activity J.Antimicrob.Chemother., 63, 2009
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2009-01-08
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