argininosuccinate <=> fumarate + arginine

This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>

本事件系基于在另一物种中已证实的事件的计算推断而来。推断过程依托于PANTHER的同源性映射。概而言之，对于所有涉及的物理实体（包括输入、输出及催化剂）均具有对应同源或旁系同源（对于复合物而言，至少75%的组分必须具有映射）的反应，均推断至另一物种。同时，对这些事件也进行了高级别事件的推断，以便利导航。有关Reactome中事件推断的更多细节及注意事项，请参阅<a href='/electronic_inference_compara.html' target = 'NEW'>此处</a>。关于PANTHER的详细信息，亦请参考<a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>。

搜集汇总

背景与挑战

背景概述

该数据集描述了Gallus gallus（鸡）物种中精氨琥珀酸裂解为精氨酸和延胡索酸的可逆生化反应，属于尿素循环代谢途径。该反应发生在细胞质中，由精氨琥珀酸裂解酶催化，是通过PANTHER同源映射从人类数据推断而来的计算推断结果。