This is a continuation of the Chordoma Sequencing Project. All cancers arise due to somatically acquired abnormalities in DNA sequence. Systematic sequencing of cancer genomes allows acquisition of co
Sequencing of LCM-derived microbiopsies from 10 women who underwent reduction mammoplasty. Goal to assess the mutational burden, spectrum, and clonal dynamics within the tissue. Exome data will be use
In order to determine the mutational burden in highly variable and lowly variable breast cancer cells, we quantified single-nucleotide variant and insertion-deletion mutation frequencies from populati
We generated paired-end panel seq data from 89 ccRCC patients, including two spatially separated primary tumor biopsies, and a matched normal sample per patient. A selection of 826 genes frequently mu
