CARM1 in complex with EML709
收藏Protein Data Bank Japan2024-01-31 更新2026-03-28 收录
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CARM1 in complex with EML709 Descriptor: 1,2-ETHANEDIOL, Histone-arginine methyltransferase CARM1, methyl 6-[4-[[~{N}-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl]carbamimidoyl]amino]butylcarbamoylamino]-4-oxidanyl-naphthalene-2-carboxylate Authors: Marechal, N, Cura, V, Bonnefond, L, Troffer-Charlier, N, Cavarelli, J. Deposit date: 2021-09-15 Release date: 2022-04-06 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.42 Å) Cite: Turning Nonselective Inhibitors of Type I Protein Arginine Methyltransferases into Potent and Selective Inhibitors of Protein Arginine Methyltransferase 4 through a Deconstruction-Reconstruction and Fragment-Growing Approach. J.Med.Chem., 65, 2022
创建时间：
2021-09-15
