Melanoma of Unknown Primary (MUP) Monocentric Retrospectivr Study

173 consecutive patients with a diagnosis of MUP referring to the Melanoma and Sarcoma Clinic of the Veneto Institute of Oncology (IOV) and the Department of Surgery Oncology and Gastroenterology (DISCOG) of the University of Padua (Italy) between 1985 and 2018 were considered for inclusion in this retrospective cohort study. 127 MUP cases were included in this study according with Das Gupta’s criteria. Continuous data were expressed as median and interquartile range (IQR). The association between medical treatments and tumor stage was evaluated using Fisher’s exact test. Survival curves were calculated using Kaplan-Meier method.1985年至2018年间，173例确诊为原发灶不明黑色素瘤（Melanoma of Unknown Primary, MUP）的连续就诊患者，因前往威尼托肿瘤研究所（Veneto Institute of Oncology, IOV）黑色素瘤与肉瘤门诊及意大利帕多瓦大学外科肿瘤学与胃肠病学系（Department of Surgery Oncology and Gastroenterology, DISCOG）就诊，被纳入本回顾性队列研究的候选对象。最终依据Das Gupta标准，共有127例MUP病例被纳入本研究。连续型数据以中位数及四分位数间距（interquartile range, IQR）表示。采用Fisher确切概率法（Fisher’s exact test）评估内科治疗与肿瘤分期之间的关联。生存曲线采用Kaplan-Meier法绘制。