five

WDR5 bound to inhibitor MM-589

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Protein Data Bank Japan2024-03-13 更新2026-03-21 收录
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WDR5 bound to inhibitor MM-589 Descriptor: 1,2-ETHANEDIOL, N-{(3R,6S,9S,12R)-6-ethyl-12-methyl-9-[3-(N'-methylcarbamimidamido)propyl]-2,5,8,11-tetraoxo-3-phenyl-1,4,7,10-tetraazacyclotetradecan-12-yl}-2-methylpropanamide, SULFATE ION, ... Authors: Stuckey, J.A. Deposit date: 2017-04-07 Release date: 2017-06-28 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.64 Å) Cite: Discovery of a Highly Potent, Cell-Permeable Macrocyclic Peptidomimetic (MM-589) Targeting the WD Repeat Domain 5 Protein (WDR5)-Mixed Lineage Leukemia (MLL) Protein-Protein Interaction. J. Med. Chem., 60, 2017
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2017-04-07
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