A genome-wide screening identified effector genes of chromatin accessibility. To investigate the functional consequences of the loss of each effector gene, we conducted Mnase-seq with eHAP cells knock
We report chromatin accessibility time-course profiling (ATAC-seq) of induced trophoblast stem cells (iTSCs) derived directly from human fibroblasts and naïve reprogramming intermediates. Overall des
The chromatin remodeller ATRX interacts with the histone chaperone DAXX, to deposit the histone variant H3.3 at sites of nucleosome turnover. ATRX is known to bind repetitive, heterochromatic regions