To complement established rational and evolutionary protein design approaches, significant efforts are being made to utilize computational modeling and the diversity of naturally occurring protein seq
T33-ml35 - Designed Tetrahedral Protein Cage Using Machine Learning Algorithms Descriptor: T33-ml35-redesigned-CutA-fold, T33-ml35-redesigned-TPR-domain-fold Authors: Castells-Graells, R, Meador, K, S
Engineering and characterizing proteins can be time-consuming and cumbersome, motivating previous efforts to develop CRISPR-Cas enzymes with generalist properties to facilitate diverse genome editing