Cryo-EM structure of the PGD2-bound prostaglandin D2 receptor (DP1)-Gs complex
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Cryo-EM structure of the PGD2-bound prostaglandin D2 receptor (DP1)-Gs complex Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... Authors: Davoudinasab, B, Cherezov, V, Han, G.W, KIm, D. Deposit date: 2024-11-08 Release date: 2025-09-03 Last modified: 2026-03-11 Method: ELECTRON MICROSCOPY (2.68 Å) Cite: Structural insights into the mechanism of activation and inhibition of the prostaglandin D2 receptor 1. Nat Commun, 16, 2025
结合前列腺素D2(PGD2)的前列腺素D2受体(DP1)-Gs复合物的冷冻电镜(Cryo-EM)结构
描述项:2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖、胆固醇半琥珀酸酯、鸟嘌呤核苷酸结合蛋白G(I)/G(S)/G(O)亚基γ-2……
作者:Davoudinasab B、Cherezov V、Han G.W、Kim D
存档日期:2024-11-08
发布日期:2025-09-03
最后修改日期:2026-03-11
实验方法:电子显微镜(分辨率2.68埃)
引用文献:《前列腺素D2受体1的激活与抑制机制的结构洞察》,《自然·通讯》(Nat Commun),2025年,第16卷。
创建时间:
2024-11-08



