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Proteomic and genomic characterization of a yeast model for Ogden syndrome [RNA-seq and Ribo-seq]

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Naa10 is a Nα-terminal acetyltransferase that, in a complex with its auxiliary subunit Naa15, co-translationally acetylates the α-amino group of newly synthetized proteins as they emerge from the ribosome

Naa10是一种Nα末端乙酰转移酶(Nα-terminal acetyltransferase),当其与辅助亚基Naa15形成复合物时,可在新生蛋白质从核糖体中透出的过程中,对其α-氨基进行共翻译乙酰化修饰。

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