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Transport of an Antifungal Trypsin Inhibitor Isolated from Corn across the Blood-Brain Barrier

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PubMed Central2026-05-16 收录
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https://pmc.ncbi.nlm.nih.gov/articles/PMC127332/
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资源简介:
We determined whether an antifungal 14-kDa protein trypsin inhibitor isolated from corn is able to cross the blood-brain barrier. We found that it completely crossed the blood-brain barrier by means of a saturable mechanism at a rate of 0.153 μl/g · min, with about 0.082% of the intravenously injected dose being taken up per gram of brain.
提供机构:
American Society for Microbiology (ASM)
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