Additional file 2: Table S1. of Long-term consequences of in utero irradiated mice indicate proteomic changes in synaptic plasticity related signalling
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Deregulated proteins found in hippocampus and cortex of in utero irradiated mice in comparison to sham-irradiated mice 6 months post-irradiation using mass spectrometry-based proteomics. Complete detailed list of deregulated proteins (name, unique peptides, n-fold-change, variability and counts per biological replicate) obtained from cortex and hippocampus 6 months after in utero irradiation at doses of 0.1, 0.5 and 1.0 Gy; n = 3. Deregulated proteins were categorised into protein classes using PANTHER classification system software and the general annotation from UniProt as indicated by an asterisk. Green highlighted proteins function as calmodulin/calmodulin protein kinases; orange ones as protein kinases and brown ones as key proteins in MAPK signalling pathway. Table S2. Mass spectrometry-based proteomics – comparison of dose-independent overlapping proteins found in hippocampus and cortex. Overlapping deregulated proteins found in hippocampus and cortex at doses of 0.1, 0.5 and 1.0 Gy are shown with protein names and fold changes; n = 3. Table S3. Antibodies used for immunoblotting. (XLS 138 kb)
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2017-12-19



