Harmonized datasets to support seroepidemiology of Trachoma for the elimination endgame

Trachoma is targeted for global elimination as a public health problem by
2030. Measurement of IgG antibodies in children is being considered for
surveillance and programmatic decision-making. There are currently no
guidelines for applications of serology, which represents a generalizable
problem in seroepidemiology and disease elimination. We collated Chlamydia
trachomatis Pgp3 and CT694 IgG measurements from 48 serosurveys, including
surveys across Africa, Latin America, and the Pacific Islands to estimate
population-level seroconversion rates (SCR) along a gradient of trachoma
endemicity.