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Expression data from 3-month-old mouse hippocampus of Ts1Cje and wild-type mice

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE160185
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The Ts1Cje mouse model of Down syndrome (DS) has partial triplication of mouse chromosome 16, of which a large portion is homologous to human chromosome 21. The mouse model shows an impaired neurogenesis in hippocampus at 3-month-old . We analyzed the effect of Ts1Cje trisomic region on global gene expression in the adult brain of Ts1Cje mice at 3-month-old. RNA was extracted from hippocampus for hybridization to arrays from 4 pairs of Ts1Cje and disomic wild-type littermate control.
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2021-08-02
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