Microbiota derived interlukin-35 producing B cells induce regulatory immune responses and supress colitis in mice

To investigate the immune regulatory role of microbiota derived interlukin-35 producing B cells in DSS-induced mice colitis. We then performed gene expression profiling analysis using data obtained from RNA-seq of isolated B cells from patches of colitis mice at four different time points. Comparative gene expression profiling analysis of RNA-seq data of B cells from patches of colitis mice at different time points (Day 0, Day 4, Day 7 and Day 10)