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PUMA-induced apoptosis in telomere biology disorders

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NIAID Data Ecosystem2026-05-10 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP590423
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Serial transplantations using WT, Puma-/- , G3 mTerc-/-Puma+/+ and G3 mTerc-/-Puma-/- donors were used to analyze the effects of PUMA deficiency on the hematological phenotype of telomerase-deficient mice. RNAseq was performed to assess how downstream signaling was affected. Overall design: Generation breeding and serial LSK cell transplantation
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2026-01-22
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