Human MTHFD2 in complex with Compound 18
收藏Protein Data Bank Japan2024-03-27 更新2026-03-21 收录
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资源简介：
Human MTHFD2 in complex with Compound 18 Descriptor: Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial, N-[2-chloranyl-4-[[7-methyl-8-(4-methylpiperazin-1-yl)-5-oxidanylidene-2,4-dihydro-1H-chromeno[3,4-c]pyridin-3-yl]carbonyl]phenyl]methanesulfonamide, ... Authors: Suzuki, M, Matsui, Y, Ota, M, Kawai, J. Deposit date: 2019-07-10 Release date: 2019-11-13 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Discovery of a Potent, Selective, and Orally Available MTHFD2 Inhibitor (DS18561882) with in Vivo Antitumor Activity. J.Med.Chem., 62, 2019
创建时间：
2019-07-10
